Deep Brain Stimulation for Parkinson's Disease: a survey of experiences perceived by recipients and carers
نویسندگان
چکیده
Perceived outcomes from DBS for PD were sampled for 52 cases by surveying 46 DBS recipients and 45 carers. Post-DBS experience ranged from 10-129 months. There were significant variations in perceived outcomes over time. In some cases extreme variations were experienced as a consequence of hardware and other problems requiring additional surgery. Nevertheless most in this group went on to ultimately report good outcomes. Holistic assessments of experiences were largely positive, but in some cases there were significant differences in the assessments by recipients and carers. For assessments valid at the time of interview 26 recipients and 17 carers commented that the outcome was good. A second group of 11 recipients and 12 carers reported mixed results but overall a positive experience. A third group of 6 recipients and 8 carers reported negatively about the outcomes. Many considered overall quality of life much better following DBS, more so recipients than carers. Post-DBS experiences of both motor and non-motor symptoms varied greatly between cases. When considering the average of participant responses, tremor and dyskinesias were considered better or much better following DBS, with benefits sustained with time. 12 months after DBS many symptoms were on average considered the same or better after DBS, but for many, some decline in benefits was apparent over this period. Some symptoms were reported to show no improvement, or be worse following DBS. 12 months after the procedure the average of participant responses indicated that symptoms including speech, postural stability, swallowing, handwriting, cognitive function and incontinence were worse.
منابع مشابه
Closed- and Open-loop Deep Brain Stimulation: Methods, Challenges, Current and Future Aspects
Deep brain stimulation (DBS) is known as the most effective technique in the treatment of neurodegenerative diseases, especially Parkinson disease (PD) and epilepsy. Relative healing and effective control of disease symptoms are the most significant reasons for the tangible tendency in use and development of this technology. Nevertheless, more cellular and molecular investigations are required ...
متن کاملThe effect of bilateral subthalamic nucleus deep brain stimulation (STN-DBS) on the acoustic and prosodic features in patients with Parkinson’s disease: A study protocol for the first trial on Iranian patients
Background: The effect of subthalamic nucleus deep brain stimulation (STN-DBS) on the voice features in Parkinson’s disease (PD) is controversial. No study has evaluated the voice features of PD underwent STN-DBS by the acoustic, perceptual, and patient-based assessments comprehensively. Furthermore, there is no study to investigate prosodic features before and after DBS in PD. The curren...
متن کاملAnatomical situation of the subthalamic nucleus (STN) from midcommissural point (MCP) in Parkinson\'s disease patients underwent deep brain stimulation (DBS): an MRI targeting study
Abstract Introduction: It is demonstrated that the degree of clinical improvement in Parkinson's disease (PD) achieved by deep brain stimulation (DBS) is largely dependent on the accuracy of lead placement. In addition, individual variability in the situation of subthalamic nucleus (STN) is responsible for spatial inter-individual fluctuations of the real patient's target. Objecti...
متن کاملControl of epileptic seizures by electrical low frequency deep brain stimulation: A review of probable mechanisms
Epilepsy is the most common neurological disease with no definitive method in treatment. Notably, the main way to treat and control epileptic seizures is drug therapy. However, about 20-30% of patients with epilepsy are drug resistant and require other therapeutic manners. Deep brain stimulation is a new therapeutic strategy for these patients. Conspicuously, there are no clear answers for basi...
متن کامل